Assessing the Effect of Genetic Mutation: A Bayesian Framework for Determining Population History from DNA Sequence Data

نویسندگان

  • S. P. Brooks
  • I. Manolopoulou
چکیده

In cases where genetic sequence data are collected together with associated physical traits it is natural to want to link patterns observed in the trait values to the underlying genealogy of the individuals. If the traits correspond to specific phenotypes, we may wish to associate specific mutations with changes observed in phenotype distributions, whereas if the traits concern spatial information, we may use the genealogy to look at population movement over time.

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تاریخ انتشار 2006